How To Get To Ithaca From NYC? The cheapest way to get from New York to Ithaca is to bus which costs $18 – $80 and takes 4h 45m. What is the fastest way to get from New York to Ithaca? The quickest way to get from New York to Ithaca is to train and fly which costs $110 – $470 and takes 3h 52m. Is there a train between NYC and Ithaca? Trip Summary There are 2 daily trains from New York to Ithaca. Traveling by train from New York to Ithaca usually takes around 9 hours and 19 minutes, but the fastest Amtrak train can make the trip…