How To Get To Cape Cod From NYC? There are 10 ways to get from Manhattan to Cape Cod by train, bus, ferry, car, subway or plane ; Take the train from New York Penn Station to Boston. The distance between Manhattan and Cape Cod is 206 miles. The road distance is 252.7 miles. The driving distance between Manhattan to Cape Cod is 253 miles. It takes approximately 4h 47m to drive from Manhattan to Cape Cod. How do you get to Cape Cod from NYC without a car? The best way to get from Manhattan to Cape Cod without a car is to train and bus which takes 6h…